VSV and Immunology
Identifying VSV genes that shorten untranslated regions of mRNA and induce immune responses
Identifying VSV genes that shorten untranslated regions of mRNA and induce immune responses
As part of the 42nd New Jersey Governor's School in Science, our team worked towards identifying the gene(s) of the Vesicular Stomatitis Virus (VSV) genome that are potentially responsible for shortening the length of human 3' untranslated regions (3' UTR). Prior research suggested that VSV shortened human 3' UTR lengths, and such changes may impact innate immune system regulations.
Thank you to the New Jersey Governor's School in Science, Drew University, Dr. Tyler Dorrity, and my teammates for this opportunity to immerse in hands-on research.